Drug Use Burden and Enforcement Indicators in Nigeria: A Retrospective Ecological Analysis
Main Article Content
Keywords
Nigeria, drug seizures, drug use burden, ecological analysis, NDLEA, surveillance
Abstract
Background: Nigeria faces a substantial burden of illicit drug use alongside intensified enforcement activity. However, the geographic correspondence between enforcement indicators and population-level drug use burden remains poorly characterised. This study provides an ecological assessment of enforcement–burden alignment in Nigeria and introduces a Total Seizure-to–Any-Drug-User Ratio (TSUR) as a policy-relevant surveillance metric.
Methodology: We conducted a retrospective ecological analysis of Nigeria’s six geopolitical zones. Drug use burden was obtained from the 2018 Drug Use in Nigeria survey; seizure, arrest, and conviction data were extracted from National Drug Law Enforcement Agency (NDLEA) reports (2021–2022). We calculated a Total Seizure-to–Any-Drug-User Ratio (TSUR; kg seized per 1,000 estimated past-year users) using 2018 survey denominators and 2021–2022 NDLEA seizure totals. Associations were assessed using Spearman’s rank correlation (n = 6 zones). To evaluate robustness to temporal mismatch, we conducted sensitivity analyses assuming ±10–20% changes in zonal prevalence.
Results: Past-year drug use prevalence ranged from 10.0% to 22.4% across zones. National seizures increased substantially between 2021 and 2022 and were dominated by cannabis by weight. TSUR varied markedly across geopolitical zones (<5 kg to >300 kg per 1,000 users), indicating substantial geographic differences in seizure intensity relative to the 2018 baseline distribution of drug users. Zone-level correlations between seizure weight and estimated users were positive but statistically unstable, given the small number of aggregate units.
Conclusions: Marked regional variation exists in both drug use burden and enforcement activity across Nigeria. Using a historical demand-side baseline and subsequent enforcement indicators, this analysis demonstrates only partial geographic concordance between seizures and estimated user burden. The TSUR provides a transparent, scalable metric for contextualising enforcement activity alongside epidemiological estimates in data-constrained settings, when interpreted cautiously.
References
2. Osayomi T, Iyanda AE, Adeleke R, Osadolor OJ. Geographical analysis of illicit drug use in Nigeria: evidence from the first national drug use survey 2018. Prof Geogr. 2021;73(3):431–446. doi:10.1080/00330124.2020.1864477
3. United Nations Office on Drugs and Crime. Bulletin on Narcotics. Volume LXII: Drugs in a Nigerian population [Internet]. Vienna: UNODC; 2019 [cited 2025 Oct 6]. Available from: https://www.unodc.org/documents/data-and-analysis/bulletin/Drugs_in_Nigerian_population.pdf
4. Gureje O, Degenhardt L, Olley BO, Uwakwe R, Udofia O, Wakil A, et al. A descriptive epidemiology of substance use and substance use disorders in Nigeria during the early 21st century. Drug Alcohol Depend. 2007;91(1):1–9.
5. National Bureau of Statistics (Nigeria). Poverty and Inequality in Nigeria 2019: Executive Summary [Internet]. Abuja: NBS; 2020 [cited 2025 Oct 6]. Available from: https://nigerianstat.gov.ng/elibrary/read/1209
6. National Bureau of Statistics (NBS). Demographic Statistics Bulletin 2022 [Internet]. Abuja: NBS; 2023 [cited 2025 Oct 6]. Available from: https://www.nigerianstat.gov.ng/pdfuploads/DEMOGRAPHIC_BULLETIN_2022_FINAL.pdf
7. World Health Organization. Tramadol: critical review report. Expert Committee on Drug Dependence, 41st meeting; 12–16 Nov 2018; Geneva. Geneva: World Health Organization; 2018.
8. Yorke E, Oyebola FO, Otene SA, Klein A. Tramadol: a valuable treatment for pain in Ghana and Nigeria. Curr Med Res Opin. 2019;35(5):777–784. doi:10.1080/03007995.2019.1585168
9. Nakhaee S, Hoyte C, Dart RC, Askari M, Lamarine RJ, Mehrpour O. A review on tramadol toxicity: mechanism of action, clinical presentation, and treatment. Forensic Toxicol. 2021;39(2):293–310. doi:10.1007/s11419-020-00569-0
10. Salm Reifferscheidt L. Tramadol: Africa’s opioid crisis. Lancet. 2018;391(10134):1982–1983. doi:10.1016/S0140-6736(18)31073-0
11. Nelson EU, Odeigah OW, Dumbili EW. Tramadol regulation, illegal markets and consumption practices: exploring frictions of drug control in Nigeria. Drugs Habits Soc Policy. 2023;24(4):296–309. doi:10.1108/DHS-12-2022-0051
12. Dumbili EW, Ezekwe RC, Odeigah OW. Enhancement motivations for using prescription drugs among young adults in Nigeria. Int J Drug Policy. 2021;95:103295.
13. United Nations Office on Drugs and Crime. Key findings of UNODC study on tramadol trafficking in West Africa discussed at regional meeting [Internet]. 2019 Jul 29 [cited 2025 Oct 6]. Available from: https://www.unodc.org/unodc/en/frontpage/2019/July/key-findings-of-unodc-study-on-tramadol-trafficking-in-west-africa-discussed-at-regional-meeting.html
14. BBC Africa Eye. Sweet Sweet Codeine: Nigeria’s cough syrup crisis [documentary]. London: BBC; 2018. Available from: https://www.youtube.com/watch?v=-I_Lche2otU [cited 2025 Oct 25].
15. Federal Ministry of Health (Nigeria). Press release: ban on codeine-containing cough syrups. Abuja: FMOH; 2018 May 1.
16. National Agency for Food and Drug Administration and Control (NAFDAC). Codeine syrup crisis: NAFDAC lifts shutdown of cough syrup production in Nigeria [Internet]. Abuja: NAFDAC; 2018 [cited 2025 Oct 6]. Available from: https://www.nafdac.gov.ng/codeine-syrup-crisis-nafdac-lifts-shutdown-of-cough-syrup-production-in-nigeria/
17. Federal Republic of Nigeria, United Nations Office on Drugs and Crime. National Drug Control Master Plan 2021–2025 [Internet]. Abuja: Federal Republic of Nigeria; 2021 [cited 2025 Oct 6]. Available from: https://www.unodc.org/documents/nigeria//National_Drug_Control_Master_Plan_2021-2025.pdf
18. National Drug Law Enforcement Agency (NDLEA). Annual Report 2021 [Internet]. Nigeria: NDLEA; 2022 [cited 2025 Oct 25]. Available from: https://ndlea.gov.ng/files/Annual%20Report%202021.pdf
19. National Drug Law Enforcement Agency. Scorecard of the NDLEA (2021–2023): War Against Drug Abuse (WADA). Nigeria: NDLEA; 2023.
20. Klantschnig G. The politics of drug control in Nigeria: exclusion, repression and obstacles to policy change. Int J Drug Policy. 2016;30:132–139. doi:10.1016/j.drugpo.2015.10.012
21. Reuter P, Pardo B. Can new data sources help improve international drug policy? Int J Drug Policy. 2017;41:182–183. doi:10.1016/j.drugpo.2017.03.006
22. United Nations Office on Drugs and Crime. World Drug Report 2023 [Internet]. Vienna: UNODC; 2023 [cited 2025 Oct 6]. Available from: https://unodc.org/unodc/en/data-and-analysis/world-drug-report-2023.html
23. United Nations Office on Drugs and Crime. World Drug Report 2025: Methodological Annex [Internet]. Vienna: UNODC; 2025 [cited 2025 Oct 6]. Available from: https://www.unodc.org/documents/data-and-analysis/WDR_2025/Annex/WDR2025_Methodological_Annex.pdf
24. Morgenstern H. Ecologic studies in epidemiology: concepts, principles, and methods. Annu Rev Public Health. 1995;16:61–81. doi:10.1146/annurev.pu.16.050195.000425
25. Greenland S, Morgenstern H. Ecological bias, confounding, and effect modification. Int J Epidemiol. 1989;18(1):269–274. doi:10.1093/ije/18.1.269
26. National Drug Law Enforcement Agency (NDLEA). Annual Report 2022 [Internet]. Nigeria: NDLEA; 2023 [cited 2025 Oct 6]. Available from: https://ndlea.gov.ng/files/Annual%20Report%202022.pdf
27. United Nations Office on Drugs and Crime (UNODC). World Drug Report 2023: Methodology [Internet]. Vienna: UNODC; 2023 [cited 2025 Oct 6]. Available from: https://www.unodc.org/unodc/en/data-and-analysis/wdr2023_annex.html
28. National Agency for Food and Drug Administration and Control (NAFDAC). Public Alert No. 008/2018: Recall of codeine-containing cough syrups [Internet]. Abuja: NAFDAC; 2018 [cited 2025 Oct 25]. Available from: https://nafdac.gov.ng/category/recalls-and-alerts/
