Association of BMI Grading with Aortic Pulse Wave Velocity and Augmentation Index in a Population of West India
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Keywords
Arterial stiffness, Body Mass Index, Diabetes Mellitus, hypertension, pulse wave velocity
Abstract
Background: BMI is graded differently in Asians, and its association with pulse wave analysis (PWA) based arterial stiffness (AS) parameters are unknown in the Indian population. We studied these AS parameters in relation to BMI grading as per ESI (Endocrine Society of India) for association, if any.
Methodology: This is a secondary pooled analysis of previously published data of normal (n=1186), diabetics (n=328), hypertensives(n=309), and diabetic hypertensives(n=401). Oscillometric PWA (Mobil-o-graph, IEM, Germany) was used to derive aortic BP (aBP), aortic pulse wave velocity (aPWV), augmentation index (AIx), and reflection %. All participants in each group were divided into BMI-based subgroups as per the ESI criteria for Indians. PWA parameters were compared among BMI-based subgroups in each of the four study groups.
Results: Aortic pressures, AIx, aPWV, and Ref% were significantly associated with BMI grading only in the normal subgroup and not in the other three groups with at least one of either diabetes or hypertension. In the multivariate linear regression model, BMI-based grading was not associated with aPWV or AIx after adjusting for gender, age, mean blood pressure, heart rate, and presence of diabetes and/or hypertension.
Conclusion: It suggests arterial stiffness to be a poorly BMI-dependent parameter and calls for more studies for its consolidation.
References
2. JD Solanki,HB Mehta, CJ Shah. Aortic pulse wave velocity and augmentation index@ 75 measured by oscillometric pulse wave analysis in Gujarati nonhypertensives. Vasc Invest Ther,1(2) (2018 Jul 1), pp.50-55
3. JD Solanki,HB Munshi,HB Mehta,CJ Shah. Central hemodynamics and arterial stiffness in Gujarati diabetics not receiving any antihypertensive: A case–control study based on oscillometric pulse wave analysis. J Family Med PrimCare,8(4) (2019 Apr 1),pp. 1352-1358
4. JD Solanki,HB Mehta,SJ Panjwani,HB Munshi,CJ Shah. Central hemodynamics and arterial stiffness by oscillometric pulse-wave analysis in treated Gujarati euglycemic hypertensives: A case-control study. J Family Med Prim Care,8(6) ( 2019 Jun 1), pp.2047-2054
5. JD Solanki,SJ Panjwani,RK Patel,DN Bhatt,PJ Kakadia ,CJ Shah. Assessment of arterial stiffness, brachial haemodynamics, and central haemodynamics in diabetic hypertensives: a pulse wave analysis-based case-control study from an urban area of west India. Pulse, 9(3-4) (2021 Oct 25), pp. 89-98
6. M Riaz,S Lodhi. Beyond BMI: Exploring obesity trends in the south Asian region. Obes Pillars,13 (2025 Mar 1), article 100156
7. SS Bajaj , A Zhong,AL Zhang,FC Stanford. Body mass index thresholds for Asians: a race correction in need of correction?. Ann Intern Med,177(8) (2024 Aug), pp.1127-1129
8. L Zhao,X Zhou,Y Chen,Q , et al. Association of visceral fat area or BMI with arterial stiffness in ideal cardiovascular health metrics among T2DM patients. J Diabetes, 16(1) ( 2024 Jan), e13463
9. B Jan,MI Dar,B Choudhary,P Basist,R Khan,A Alhalmi Cardiovascular diseases among Indian older adults: A comprehensive review. Cardiovas Ther,2024(1) (2024) Article 6894693
10. HJ Kim, JH Shin,BS Kim,J Kang,H Lee, KC Sung. Age-related annual changes in arterial stiffness in healthy adults: Insights from a large Korean cohort study. Atheroscler,398 (2024 Nov 1), Article 118592
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